Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.65 |
| ▸ | MAOA | P21397 | 5/20 | 0.65 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019357 | 1.00 | KDM1A (0.65) | KDM1AMAOAMAOB | |
| SCHEMBL12886008 | 1.00 | KDM1A (0.65) | KDM1AMAOAMAOB | |
| SCHEMBL15778147 | 0.85 | KDM1A (0.61) | KDM1AMAOAMAOB | |
| SCHEMBL25069768 | 0.84 | KDM1A (0.62) | KDM1AMAOAMAOB | |
| SCHEMBL25069673 | 0.82 | KDM1A (0.46) | KDM1AMAOAMAOB | |
| SCHEMBL25069676 | 0.82 | KDM1A (0.46) | KDM1AMAOAMAOB | |
| SCHEMBL15778201 | 0.81 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL15777424 | 0.81 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL4129699 | 0.80 | KDM1A (0.65) | KDM1AMAOAMAOB | |
| SCHEMBL4129698 | 0.80 | KDM1A (0.65) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548870-B2 | Compounds useful as inhibitors of helios protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-10 | — | — | US | disclosed |
| WO-2021101919-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20210147383-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | BRISTOL-MYERS SQUIBB COMPANY | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147383-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | IKZF2, RPL6, HNRNPR | KDM1A 1514/4885MAOA 4830/4885MAOB 4667/4885 |
| US-11548870-B2 | Compounds useful as inhibitors of helios protein | IKZF2, RPL6, HNRNPR | KDM1A 1514/4885MAOA 4830/4885MAOB 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.