Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334151 | 0.86 | GCK (1.00) | GCKGRM5 | |
| SCHEMBL13439335 | 0.82 | GCK (1.00) | GCK | |
| Hydrochloric Acid SCHEMBL2337283 | 0.81 | GCK (0.98) | GCK | |
| SCHEMBL2340410 | 0.81 | GCK (0.81) | GCK | |
| SCHEMBL2342208 | 0.81 | GCK (0.81) | GCK | |
| SCHEMBL2334403 | 0.81 | GCK (0.84) | GCK | |
| SCHEMBL2344343 | 0.80 | GCK (0.80) | GCK | |
| SCHEMBL13439401 | 0.80 | GCK (0.80) | GCK | |
| Hydrochloric Acid SCHEMBL3613296 | 0.80 | GCK (0.80) | GCK | |
| SCHEMBL13439337 | 0.80 | GCK (0.80) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948652-B1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2011-08-24 | — | — | EP | disclosed |