SCHEMBL2337574

SCHEMBL2337574

COC(=O)C1(F)CCC(N)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337572 1.00 NPSR1 (0.32) NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL18208987 0.89 NPSR1 (0.34) NPSR1MAPT
SCHEMBL28540820 0.89 NPSR1 (0.34) NPSR1MAPT
SCHEMBL31730819 0.84 NPSR1 (0.32) NPSR1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL25253267 0.82 NPSR1 (0.31) NPSR1
SCHEMBL29213559 0.79 NPSR1 (0.33) NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL1962926 0.76 GRM4 (0.35) ALDH1A1
SCHEMBL1963556 0.76 NPSR1 (0.33) NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL1962856 0.76 NPSR1 (0.33) NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL2340414 0.76 NPSR1 (0.33) NPSR1MAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110207704-A1 Novel Oxadiazole Compounds ABBOTT LABORATORIES (US) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207704-A1 Novel Oxadiazole Compounds S1PR3, S1PR1, S1PR2 NPSR1 472/4885MAPT 4556/4885ALDH1A1 4044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.