Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23377619 | 0.90 | OGA (0.34) | OGA | |
| SCHEMBL23377624 | 0.88 | GRIN1 (0.39) | OGAPIK3CDPIK3CA | |
| SCHEMBL23377475 | 0.87 | OGA (0.37) | OGA | |
| SCHEMBL23377620 | 0.86 | OGA (0.36) | OGA | |
| SCHEMBL23377474 | 0.86 | OGA (0.33) | OGA | |
| SCHEMBL23377816 | 0.85 | GRIN1 (0.33) | OGA | |
| SCHEMBL23377609 | 0.85 | OGA (0.38) | OGA | |
| SCHEMBL23377610 | 0.84 | OGA (0.32) | OGA | |
| SCHEMBL23377491 | 0.84 | OGA (0.35) | OGA | |
| SCHEMBL23377479 | 0.83 | OGA (0.34) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094312-A1 | PYRROLIDINE AND BICYCLOHETEROARYL CONTAINING OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-20 | — | — | WO | disclosed |