Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.69 |
| ▸ | CLK1 | P49759 | 4/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TLR5 | O60602 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164810 | 0.84 | LIMK1 (0.52) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL23378544 | 0.81 | PIK3CA (0.59) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL23378415 | 0.81 | LIMK1 (0.50) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL9042411 | 0.76 | CLK1 (0.67) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL30093319 | 0.76 | CLK1 (0.67) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL23378453 | 0.75 | LIMK1 (0.44) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL23378174 | 0.74 | LIMK1 (0.43) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL7991134 | 0.72 | PIK3CA (0.45) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL25662796 | 0.72 | LIMK1 (0.56) | LIMK1CLK1CDC7DBF4PIK3CA | |
| SCHEMBL16919875 | 0.71 | CLK1 (0.55) | LIMK1CLK1CDC7DBF4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021095032-A1 | GLUCOSE UPTAKE INHIBITORS AND USES THEREOF | METABOMED LTD (IL) | 2021-05-20 | — | — | WO | disclosed |