Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 18/20 | 0.60 |
| ▸ | VEGFA | P15692 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23378617 | 0.89 | EPAS1 (0.72) | EPAS1VEGFA | |
| SCHEMBL23378660 | 0.82 | EPAS1 (0.55) | EPAS1VEGFA | |
| SCHEMBL23378513 | 0.81 | EPAS1 (0.55) | EPAS1VEGFA | |
| SCHEMBL23378665 | 0.81 | EPAS1 (0.64) | EPAS1VEGFA | |
| SCHEMBL21005224 | 0.77 | EPAS1 (0.67) | EPAS1VEGFA | |
| SCHEMBL21432429 | 0.75 | EPAS1 (0.68) | EPAS1VEGFA | |
| SCHEMBL21005531 | 0.75 | EPAS1 (0.68) | EPAS1VEGFA | |
| SCHEMBL18688485 | 0.75 | EPAS1 (0.68) | EPAS1VEGFA | |
| SCHEMBL24317207 | 0.75 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL26813176 | 0.75 | EPAS1 (1.00) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021093724-A1 | NOVEL 2,3-HYDRINDENE DERIVATIVE COMPOUND, PREPARATION METHOD AND APPLICATION | 武汉光谷亚太医药研究院有限公司 | 2021-05-20 | — | — | WO | disclosed |