⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473398 | 0.97 | TRIM24 (0.40) | — | |
| SCHEMBL3882820 | 0.97 | TRIM24 (0.40) | — | |
| SCHEMBL9415911 | 0.97 | TRIM24 (0.40) | — | |
| SCHEMBL1023703 | 0.97 | — | — | |
| SCHEMBL2829 | 0.90 | — | — | |
| SCHEMBL5856682 | 0.75 | — | — | |
| SCHEMBL5855783 | 0.75 | — | — | |
| SCHEMBL5856708 | 0.71 | — | — | |
| SCHEMBL1585674 | 0.71 | — | — | |
| SCHEMBL9020773 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 39144 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043623-B2 | Purinones as ubiquitin-specific protease 1 inhibitors | FORMA THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | claimed |
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | claimed |
| WO-2024141004-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND THE USE THEREOF | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2024-07-04 | — | — | WO | claimed |
| CN-114174279-B | Bicyclic heterocyclic compounds useful as IRAK4 inhibitors | 百时美施贵宝公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118265707-A | Pesticidally active pyridazinone compounds | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | claimed |
| WO-2024133551-A1 | PESTICIDALLY ACTIVE PYRIDAZINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | claimed |
| US-20240208936-A1 | EAAT2 ACTIVATORS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2024-06-27 | — | — | US | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| US-20240199621-A1 | MAP4K4 INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LTD (GB) | 2024-06-20 | — | — | US | claimed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | claimed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | claimed |
| US-4824472-A | Herbicidal polycyclyl substituted 1H-imidazole-5-carboxylic acids | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-04-25 | — | — | US | claimed |
| US-4816454-A | CARDIOVASCULAR DISORDERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | claimed |
| EP-0277387-A2 | 1-Cyclyl or polycyclyl substituted 1H-imidazole-5-carboxylic acids | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-10 | — | — | EP | claimed |
| EP-0277384-A2 | 1H-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-10 | — | — | EP | claimed |
| EP-0273531-A1 | 1-Methyl-1h-imidazole-5-carboxylic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-07-06 | — | — | EP | claimed |
| US-4632695-A | N-phenylsulfonyl-N'-triazinylureas as herbicides and plant growth regulants | CIBA-GEIGY CORPORATION (US) | 1986-12-30 | — | — | US | claimed |
| EP-0175363-A2 | 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1986-03-26 | — | — | EP | claimed |
| US-4545806-A | 5-(Oxo or thio heterocycle) cyclohexane-1,3-dione derivatives and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-08 | — | — | US | claimed |
| EP-0058779-B1 | CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | claimed |