SCHEMBL233859

SCHEMBL233859

Cn1cc(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.56
EPHX2 P34913 1/20 0.54
SLC5A2 P31639 7/20 0.53
SLC5A1 P13866 4/20 0.51
SLC28A3 Q9HAS3 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TYR P14679 2/20 0.48
ACHE P22303 1/20 0.47
CD209 Q9NNX6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17439159 1.00 ATM (0.56) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL19846979 1.00 ATM (0.56) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL6561299 1.00 ATM (0.56) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL19854889 1.00 ATM (0.56) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL29461029 1.00 ATM (0.56) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL3191173 1.00 ATM (0.56) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL3648218 0.85 SLC5A2 (0.42) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL22412720 0.85 SLC5A2 (0.42) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL19846978 0.83 SLC28A3 (0.54) ATMEPHX2SLC5A2SLC5A1SLC28A3
SCHEMBL8516031 0.83 KMT2A (0.51) ATMEPHX2SLC5A2SLC5A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596119-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS Advanced Cell Technology, Inc. (US) 2013-05-29 EP claimed
WO-2012012803-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS ADVANCED CELL TECHNOLOGY, INC. (US) 2012-01-26 WO claimed
US-20090068696-A1 COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS STATENS SERUM INSTITUT 2009-03-12 US claimed
US-20240212150-A1 MATERIALS AND METHODS RELATED TO IMAGE PROCESSING ADVANCED CELL DIAGNOSTICS, INC. 2024-06-27 US disclosed
US-20240209423-A1 METHODS AND COMPOSITIONS FOR REDUCING AUTOFLUORESCENCE ADVANCED CELL DIAGNOSTICS, INC. 2024-06-27 US disclosed
EP-4376887-A2 MATERIALS AND METHODS OF MAKING OR USING IL-23R BINDING PROTEINS Janssen Biotech, Inc. (US) 2024-06-05 EP disclosed
WO-2024026253-A1 METHODS FOR TREATING PATIENTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND 191P4D12 PROTEINS IN COMBINATION WITH PEMBROLIZUMAB AGENSYS, INC. (US) 2024-02-01 WO disclosed
US-20240026419-A1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITION OF CELLS ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2024-01-25 US disclosed
US-20230364254-A1 METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS AGENSYS, INC. (US) 2023-11-16 US disclosed
US-20230330251-A1 METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS AGENSYS, INC. (US) 2023-10-19 US disclosed
US-11788124-B2 Methods to further enhance signal amplification for the in situ detection of nucleic acids ADVANCED CELL DIAGNOSTICS, INC. (US) 2023-10-17 US disclosed
EP-0897428-B2 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR SCIENT INC (US) 2011-07-13 EP disclosed
EP-2181330-A1 COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS Statens Serum Institut (DK) 2010-05-05 EP disclosed
US-20090068696-A1 COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS STATENS SERUM INSTITUT 2009-03-12 US disclosed
WO-2009026920-A1 COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS STATENS SERUM INSTITUT (DK) 2009-03-05 WO disclosed
EP-0897428-B1 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR SCIENT INC (US) 2007-06-06 EP disclosed
EP-0897428-A4 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR SCIENT INC (US) 2003-05-07 EP disclosed
EP-0897428-A1 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR Scientific, Inc. (US) 1999-02-24 EP disclosed
US-5726031-A Test media and quantitative method for identification and differentiation of biological materials in a test sample RCR SCIENTIFIC, INC. (US) 1998-03-10 US disclosed
WO-1997036001-A1 TEST MEDIA AND QUANTITATIVE METHOD FOR IDENTIFICATION AND DIFFERENTIATION OF BIOLOGICAL MATERIALS IN A TEST SAMPLE RCR SCIENTIFIC, INC. (US) 1997-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330251-A1 METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS CD2BP2, IGSF11, DNAH12 ATM 4106/4885EPHX2 3552/4885SLC5A2 3872/4885
US-20230364254-A1 METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS NECTIN4, CD2BP2, CD22 ATM 4466/4885EPHX2 4133/4885SLC5A2 2012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.