Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ADA | P00813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480585 | 0.84 | KDR (0.40) | KDRADORA1ADORA2AADORA3ADA | |
| SCHEMBL14365195 | 0.82 | KDR (0.36) | KDRADORA1ADORA2AADORA3 | |
| SCHEMBL10005844 | 0.76 | KDR (0.57) | KDRADORA1ADORA2AADORA3ADA | |
| SCHEMBL13061229 | 0.73 | ADORA1 (0.38) | KDRADORA1ADORA2AADORA3 | |
| SCHEMBL25643051 | 0.73 | ADORA1 (0.35) | KDRADORA1ADORA2AADORA3 | |
| SCHEMBL2077726 | 0.72 | ADORA2A (0.53) | KDRADORA1ADORA2AADORA3 | |
| SCHEMBL23386766 | 0.69 | ADORA1 (0.35) | KDRADORA1ADORA2AADORA3 | |
| SCHEMBL28058994 | 0.65 | — | — | |
| SCHEMBL23480679 | 0.64 | KDR (0.36) | KDR | |
| SCHEMBL14365366 | 0.64 | KDR (0.51) | KDRADORA1ADORA2AADORA3ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021096860-A1 | MCL1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2021-05-20 | — | — | WO | disclosed |