Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.68 |
| ▸ | ACACB | O00763 | 2/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23387375 | 1.00 | NOTUM (0.68) | NOTUMACACBCCNCCDK8TAS1R3 | |
| SCHEMBL22499837 | 0.84 | NOTUM (0.57) | NOTUMACACB | |
| SCHEMBL21625629 | 0.82 | NOTUM (0.55) | NOTUMACACB | |
| SCHEMBL21625630 | 0.82 | NOTUM (0.55) | NOTUMACACB | |
| SCHEMBL3931285 | 0.81 | USP30 (0.49) | NOTUMUSP30 | |
| SCHEMBL3931291 | 0.81 | USP30 (0.49) | NOTUMUSP30 | |
| SCHEMBL21624686 | 0.81 | NOTUM (0.53) | NOTUMACACBCCNCCDK8 | |
| SCHEMBL21624688 | 0.81 | NOTUM (0.53) | NOTUMACACBCCNCCDK8 | |
| SCHEMBL23387314 | 0.81 | NOTUM (0.64) | NOTUMUSP30 | |
| SCHEMBL23387267 | 0.81 | NOTUM (0.64) | NOTUMUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825303-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nippon Chemiphar Co., Ltd. (JP) | 2021-05-26 | — | — | EP | disclosed |