Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29689797 | 0.83 | USP30 (0.53) | RORCCACNA1GCACNA1HCACNA1I | |
| SCHEMBL21624785 | 0.77 | USP30 (0.49) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL21624784 | 0.77 | USP30 (0.49) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL23387269 | 0.75 | CYP3A4 (0.47) | POLBLMNARORCCACNA1GCACNA1H | |
| SCHEMBL31332321 | 0.72 | USP30 (0.34) | — | |
| SCHEMBL23387172 | 0.72 | ACACB (0.40) | CACNA1GCACNA1HCACNA1ISIGMAR1 | |
| SCHEMBL23387284 | 0.69 | HRH3 (0.43) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL21199564 | 0.68 | DPP4 (0.55) | ALDH1A1 | |
| SCHEMBL21199008 | 0.68 | DPP4 (0.55) | ALDH1A1 | |
| SCHEMBL16740675 | 0.68 | DPP4 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825303-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nippon Chemiphar Co., Ltd. (JP) | 2021-05-26 | — | — | EP | disclosed |