SCHEMBL233914

SCHEMBL233914

CCCCN[Si](NCCCC)(NCCCC)NCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
ALDH1A1 P00352 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
ADH7 P40394 2/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
LMNA P02545 1/20 0.38
EPHX1 P07099 5/20 0.36
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
ACHE P22303 1/20 0.32
MMP2 P08253 1/20 0.32
ADH4 P08319 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234957 0.94 TSHR (0.41) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL235198 0.94 TSHR (0.41) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL234260 0.91 TSHR (0.46) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL233669 0.91 TSHR (0.46) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL233188 0.91 TSHR (0.46) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL234029 0.88 EPHX1 (0.52) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL9816794 0.88 EPHX1 (0.52) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL235154 0.85 TSHR (0.39) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL233202 0.85 TSHR (0.39) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL236131 0.79 TSHR (0.35) TSHRALDH1A1CA1CA2ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
EP-1908767-B1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME TOHO TITANIUM CO LTD (JP) 2012-06-13 EP disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed
US-20100190942-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME TOHO CATALYST CO., LTD. (JP) 2010-07-29 US disclosed
EP-1908767-A1 AMINOSILANE COMPOUNDS, CATALYST COMPONENTS AND CATALYSTS FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS WITH THE SAME Toho Catalyst Co., Ltd. (JP) 2008-04-09 EP disclosed
EP-0316696-B1 Organopolysiloxane elastomers having improved electrical properties and insulators coated therewith WACKER CHEMIE GMBH (DE) 1995-07-19 EP disclosed
EP-0543292-B1 A flame retardant elastomeric composition WACKER CHEMIE GMBH (DE) 1995-02-08 EP disclosed
US-5260372-A Polysilxoanes WACKER SILICONES CORPORATION (US) 1993-11-09 US disclosed
EP-0543292-A1 A flame retardant elastomeric composition WACKER-CHEMIE GMBH (DE) 1993-05-26 EP disclosed
EP-0316696-A2 Organopolysiloxane elastomers having improved electrical properties and insulators coated therewith WACKER-CHEMIE GMBH (DE) 1989-05-24 EP disclosed
US-4822830-A CROSSLINKED WITH AMINOORGANOSILICON COMPOUND AND ALUMINA TRIHYDRATE; MOISTURE CURED WACKER SILICONES CORPORATION (US) 1989-04-18 US disclosed
EP-0154723-B1 RADIATION POLYMERIZABLE COMPOSITIONS Wacker Silicones Corporation (US) 1988-03-16 EP disclosed
US-4671933-A Method for inhibiting corrosion of metal surfaces STAUFFER-WACKER SILICONES CORPORATION (US) 1987-06-09 US disclosed
EP-0154723-A1 Radiation polymerizable compositions Wacker Silicones Corporation (US) 1985-09-18 EP disclosed
US-4526955-A Organopolysiloxane having nitrogen containing group linked to silicon and free radical generating compound SWS SILICONES CORPORATION (US) 1985-07-02 US disclosed