Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336367 | 0.90 | JAK3 (0.55) | JAK3SYK | |
| SCHEMBL12450079 | 0.81 | JAK3 (0.43) | JAK3 | |
| SCHEMBL2343358 | 0.80 | JAK3 (0.48) | JAK3SYK | |
| SCHEMBL2341558 | 0.77 | JAK3 (0.55) | JAK3 | |
| SCHEMBL2336764 | 0.77 | JAK3 (0.55) | JAK3 | |
| SCHEMBL2340467 | 0.76 | JAK3 (0.48) | JAK3 | |
| SCHEMBL2342183 | 0.74 | JAK3 (0.57) | JAK3 | |
| SCHEMBL1633670 | 0.74 | JAK3 (0.56) | JAK3 | |
| SCHEMBL1890379 | 0.74 | JAK3 (0.67) | JAK3 | |
| SCHEMBL1369300 | 0.74 | JAK3 (0.75) | JAK3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250172-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-08-31 | — | — | EP | claimed |