Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11994444 | 0.86 | MAPT (0.50) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL22672251 | 0.86 | ALOX5AP (0.65) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL30204004 | 0.86 | ALOX5AP (0.65) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL30203975 | 0.86 | HSP90AB1 (0.62) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL22672262 | 0.86 | HSP90AB1 (0.62) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL2947037 | 0.84 | MAPT (0.66) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL30203871 | 0.84 | MAPT (0.66) | GPR55CNR1CNR2MAPTALOX5 | |
| SCHEMBL29514833 | 0.80 | HTT (0.62) | GPR55CNR1CNR2MAPTMEN1 | |
| SCHEMBL11994084 | 0.78 | MAPT (0.79) | CNR2MAPTALOX5ALOX5APMEN1 | |
| SCHEMBL13905681 | 0.78 | MAPT (0.69) | MAPTALOX5ALOX5APMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3827825-A1 | USE OF 3, 4-DIARYLPYRAZOLES AS ANTIBACTERIAL AGENTS | Wageningen Universiteit (NL) | 2021-06-02 | — | — | EP | claimed |
| EP-3827825-A1 | USE OF 3, 4-DIARYLPYRAZOLES AS ANTIBACTERIAL AGENTS | Wageningen Universiteit (NL) | 2021-06-02 | — | — | EP | disclosed |