Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.67 |
| ▸ | TXK | P42681 | 1/20 | 0.56 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.56 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373979 | 0.93 | SYK (0.74) | SYKTXKKARS1SLK | |
| SCHEMBL373563 | 0.90 | SYK (0.80) | SYKTXKKARS1SLK | |
| SCHEMBL373742 | 0.83 | SYK (0.71) | SYKTXKKARS1SLK | |
| SCHEMBL588835 | 0.82 | SYK (0.73) | SYKTXKKARS1SLK | |
| SCHEMBL373599 | 0.81 | SYK (0.88) | SYKTXKKARS1SLK | |
| SCHEMBL589047 | 0.81 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL13406834 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL27969341 | 0.80 | SYK (0.83) | SYKTXKKARS1SLK | |
| SCHEMBL374177 | 0.80 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL13406836 | 0.79 | SYK (1.00) | SYKTXKKARS1SLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424534-B1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MEDIATED DISEASES | VERTEX PHARMA (US) | 2021-06-02 | — | — | EP | disclosed |