SCHEMBL23398372

SCHEMBL23398372

CCCCn1nc(O)c(-c2ccccc2)c1-c1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 1/20 0.47
PTGIR P43119 1/20 0.44
MEN1 O00255 2/20 0.42
CYP1A2 P05177 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
CNR1 P21554 1/20 0.40
ALDH1A1 P00352 1/20 0.40
ESR1 P03372 1/20 0.39
CNR2 P34972 1/20 0.39
CYP2C9 P11712 1/20 0.39
CRHBP P24387 1/20 0.39
CYP2C19 P33261 1/20 0.39
CRHR2 Q13324 1/20 0.39
HSD11B1 P28845 2/20 0.39
HSF1 Q00613 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
SLC9A1 P19634 1/20 0.38
MPO P05164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398848 1.00 NR1H3 (0.47) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23400463 0.95 NR1H3 (0.38) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23402089 0.93 PTGIR (0.49) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23398644 0.92 CNR1 (0.42) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23401779 0.92 CNR1 (0.42) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23403179 0.89 TP53 (0.42) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23400612 0.87 TP53 (0.45) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23400242 0.86 HTR2A (0.42) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23401143 0.86 HTR2A (0.42) NR1H3PTGIRMEN1CYP1A2KMT2A
SCHEMBL23402997 0.86 ESR1 (0.38) PTGIRMEN1CYP1A2KMT2ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed