Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23399335 | 1.00 | TDP1 (0.44) | TDP1PDE1APDE1BPDE1CESR1 | |
| SCHEMBL23399190 | 0.94 | SRC (0.40) | TDP1ESR1KMT2AMEN1RAB9A | |
| SCHEMBL23402056 | 0.92 | KMT2A (0.45) | PDE1APDE1BPDE1CESR1KMT2A | |
| SCHEMBL23403476 | 0.87 | SRC (0.48) | ESR1KMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL23400978 | 0.85 | SRC (0.49) | PDE1APDE1BPDE1CESR1KMT2A | |
| SCHEMBL23400707 | 0.84 | MAPT (0.40) | TDP1PDE1APDE1BPDE1CESR1 | |
| SCHEMBL23399642 | 0.81 | SMN1; SMN2 (0.48) | TDP1KMT2ASMN1; SMN2POLBMEN1 | |
| SCHEMBL23403034 | 0.81 | SMN1; SMN2 (0.48) | TDP1KMT2ASMN1; SMN2POLBMEN1 | |
| SCHEMBL23400735 | 0.81 | TDP1 (0.46) | TDP1PDE1APDE1BPDE1CESR1 | |
| SCHEMBL23403434 | 0.80 | CCNA2 (0.49) | TDP1KMT2ASMN1; SMN2MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |