Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23400280 | 0.92 | TLR8 (0.38) | PDE5AUSP2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL23400287 | 0.88 | HEXA (0.40) | PDE5ANPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL23399297 | 0.86 | ESR1 (0.38) | PDE5AUSP2ALDH1A1MAPTMEN1 | |
| SCHEMBL23401536 | 0.84 | USP2 (0.36) | PDE5ARAB9AUSP2SMN1; SMN2MAPT | |
| SCHEMBL23399330 | 0.83 | NR1H3 (0.38) | PDE5AUSP2ALDH1A1MAPTMEN1 | |
| SCHEMBL23399309 | 0.83 | USP2 (0.50) | PDE5AUSP2ALDH1A1MAPTKMT2A | |
| SCHEMBL23400076 | 0.82 | USP2 (0.35) | PDE5ARAB9AUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL23399951 | 0.81 | HPGD (0.36) | NPC1RAB9AUSP2SMN1; SMN2MAPT | |
| SCHEMBL11965011 | 0.81 | PDE5A (0.44) | PDE5ANPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL23402927 | 0.81 | USP2 (0.38) | PDE5ARAB9AUSP2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |