SCHEMBL23399271

SCHEMBL23399271

Cc1ccc(-c2nn(C(C)C)c(-c3ccccc3C)c2O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 1/20 0.42
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
PDE1A P54750 1/20 0.36
PDE1B Q01064 1/20 0.36
PDE1C Q14123 1/20 0.36
ESR1 P03372 2/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
PIK3CD O00329 2/20 0.34
ABL1 P00519 2/20 0.34
EGFR P00533 2/20 0.34
HCK P08631 2/20 0.34
SRC P12931 2/20 0.34
KDR P35968 2/20 0.34
PIK3CA P42336 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398502 0.92 PDE1A (0.43) TP53POLBMAPTHTR2AHTR2C
SCHEMBL23400735 0.85 TDP1 (0.46) POLBMAPTHTR2AHTR2CHTR2B
SCHEMBL23400786 0.85 TDP1 (0.46) POLBMAPTHTR2AHTR2CHTR2B
SCHEMBL23401165 0.84 HTR2A (0.47) HTR2AHTR2CHTR2BTDP1ESR1
SCHEMBL23401685 0.83 MAPT (0.46) TP53POLBMAPTTDP1KMT2A
SCHEMBL23402530 0.81 HTR2A (0.38) TP53POLBMAPTHTR2AHTR2C
SCHEMBL23402420 0.80 PDE1A (0.39) TP53MAPTHTR2AHTR2CHTR2B
SCHEMBL23400659 0.80 CCNA2 (0.48) TP53POLBMAPTTDP1KMT2A
SCHEMBL23400575 0.80 CCNA2 (0.45) TP53POLBMAPTESR1KMT2A
SCHEMBL23400707 0.80 MAPT (0.40) TP53POLBMAPTHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed