SCHEMBL23399716

SCHEMBL23399716

Cc1cccc(-c2c(-c3ccccc3)c(O)nn2C(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
SRC P12931 1/20 0.40
CNR2 P34972 4/20 0.39
CNR1 P21554 3/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 1/20 0.37
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
TP53 P04637 1/20 0.36
PDE1A P54750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402570 0.93 SRC (0.39) TSHRNPSR1SRCCNR2CNR1
SCHEMBL23399698 0.87 HTR2A (0.46) TSHRSMN1; SMN2HPGDKMT2AHTR2A
SCHEMBL23403364 0.86 HTR2A (0.43) NPSR1ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL23400997 0.86 HTR2A (0.43) NPSR1ALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL23400476 0.84 SRC (0.42) TSHRSRCALDH1A1SMN1; SMN2NPC1
SCHEMBL23398539 0.81 TSHR (0.43) TSHRNPSR1CNR2CNR1ALDH1A1
SCHEMBL23399981 0.81 SRC (0.45) TSHRNPSR1SRCCNR2CNR1
SCHEMBL23400953 0.79 HTR2A (0.47) SRCALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL23400978 0.79 SRC (0.49) TSHRNPSR1SRCCNR2CNR1
SCHEMBL23398999 0.79 NPC1 (0.51) TSHRNPSR1CNR2CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed