SCHEMBL23400765

SCHEMBL23400765

CCCn1nc(CC)c(O)c1-c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.38
MAPT P10636 4/20 0.37
ADORA2A P29274 1/20 0.36
ADORA2B P29275 1/20 0.36
HEXA P06865 1/20 0.36
HEXB P07686 1/20 0.36
ALDH1A1 P00352 6/20 0.35
CNR1 P21554 1/20 0.35
KDM4E B2RXH2 4/20 0.33
HPGD P15428 2/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
CYP2D6 P10635 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403618 0.91 NR1H3 (0.38) ESR1MAPTALDH1A1CNR1TP53
SCHEMBL23401544 0.89 MAPT (0.40) ESR1MAPTADORA2AADORA2BALDH1A1
SCHEMBL23398947 0.88 MAPT (0.42) ESR1MAPTADORA2AADORA2BALDH1A1
SCHEMBL23399225 0.87 MAPT (0.41) MAPTADORA2AHEXAHEXBALDH1A1
SCHEMBL23400102 0.86 MAPT (0.44) ESR1MAPTADORA2ACNR1KDM4E
SCHEMBL23402410 0.85 HPGD (0.36) ESR1MAPTADORA2AADORA2BALDH1A1
SCHEMBL23400505 0.84 ADORA2A (0.41) ESR1MAPTADORA2AADORA2BALDH1A1
SCHEMBL23402785 0.84 GRM5 (0.39) ESR1MAPTHEXAHEXBALDH1A1
SCHEMBL23400206 0.83 ESR1 (0.48) ESR1MAPTADORA2AADORA2BALDH1A1
SCHEMBL23398607 0.82 HEXA (0.34) MAPTHEXAHEXBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed