SCHEMBL23401210

SCHEMBL23401210

CCCCn1nc(O)c(C)c1-c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 1/20 0.52
CNR1 P21554 2/20 0.49
TSHR P16473 1/20 0.47
CNR2 P34972 1/20 0.47
MEN1 O00255 2/20 0.47
CYP1A2 P05177 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 1/20 0.47
HSF1 Q00613 1/20 0.45
CYP2C9 P11712 1/20 0.43
CRHBP P24387 1/20 0.43
CYP2C19 P33261 1/20 0.43
CRHR2 Q13324 1/20 0.43
SLC9A1 P19634 1/20 0.42
MPO P05164 2/20 0.41
ESR1 P03372 1/20 0.40
PTGIR P43119 1/20 0.40
HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401631 0.91 CNR1 (0.52) NR1H3CNR1TSHRCNR2MEN1
SCHEMBL23401042 0.88 CNR1 (0.41) NR1H3CNR1CNR2MEN1CYP1A2
SCHEMBL23399614 0.86 TP53 (0.45) NR1H3CNR1TSHRCNR2MEN1
SCHEMBL23400958 0.85 NR1H3 (0.50) NR1H3CNR1TSHRCNR2MEN1
SCHEMBL23402089 0.85 PTGIR (0.49) NR1H3CNR1TSHRCNR2MEN1
SCHEMBL23401075 0.84 HTR2A (0.47) NR1H3CNR1MEN1KMT2AMAPT
SCHEMBL23402666 0.84 NR1H3 (0.48) NR1H3CNR1TSHRCNR2MEN1
SCHEMBL23399610 0.83 NR1H3 (0.54) NR1H3CNR1TSHRCNR2MEN1
SCHEMBL23402865 0.82 NR1H3 (0.40) NR1H3CNR1TSHRMEN1CYP1A2
SCHEMBL23400887 0.82 NR1H3 (0.47) NR1H3CNR1TSHRCNR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed