SCHEMBL23401294

SCHEMBL23401294

COc1ccc(-n2nc(-c3ccc(C)cc3)c(O)c2CC(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCKAR P32238 9/20 0.45
TP53 P04637 1/20 0.44
CNR1 P21554 1/20 0.41
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
CFTR P13569 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23403127 0.91 ESR1 (0.39) CCKARTP53CNR1PTGS1PTGS2
SCHEMBL23402556 0.89 RPA1 (0.44) CCKARCNR1PTGS1PTGS2
SCHEMBL23401977 0.86 TP53 (0.47) CCKARTP53CNR1PTGS1PTGS2
SCHEMBL23402291 0.85 MEN1 (0.41) CNR1
SCHEMBL23401099 0.85 KMT2A (0.44) CNR1PTGS1
SCHEMBL23400495 0.84 TP53 (0.45) CCKARTP53CNR1PTGS1PTGS2
SCHEMBL23402968 0.83 CCKAR (0.45) CCKARPTGS1PTGS2CFTR
SCHEMBL23398876 0.82 TP53 (0.43) CCKARTP53CNR1PTGS1PTGS2
SCHEMBL23403588 0.82 PDE4D (0.46) CCKARPTGS1PTGS2
SCHEMBL23398954 0.81 TP53 (0.47) CCKARTP53CNR1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed