SCHEMBL23401535

SCHEMBL23401535

CCCCc1[nH]n(-c2ccccc2C)c(=O)c1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.58
DCTPP1 Q9H773 1/20 0.46
GAA P10253 3/20 0.43
ALOX15 P16050 1/20 0.43
SLC11A2 P49281 4/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401525 0.92 KDM4E (0.49) KDM4EDCTPP1GAAALOX15SLC11A2
SCHEMBL23403304 0.87 KDM4E (0.55) KDM4EDCTPP1GAAALOX15SLC11A2
SCHEMBL23400199 0.84 KDM4E (0.40) KDM4EDCTPP1GAAMAPTHTT
SCHEMBL23402946 0.84 KDM4E (0.40) KDM4EDCTPP1GAAMAPTHTT
SCHEMBL23400374 0.84 KDM4E (0.63) KDM4EDCTPP1GAAALOX15MEN1
SCHEMBL23400478 0.82 KDM4E (0.58) KDM4EDCTPP1GAAALOX15SLC11A2
SCHEMBL23402418 0.82 KDM4E (0.40) KDM4EDCTPP1GAAMAPTHTT
SCHEMBL23402076 0.82 KDM4E (0.39) KDM4EDCTPP1GAAMAPTHTT
SCHEMBL23401241 0.81 GAA (0.43) KDM4EGAAALOX15SLC11A2MEN1
SCHEMBL23402590 0.80 KDM4E (0.38) KDM4EDCTPP1GAAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed