SCHEMBL2340331

SCHEMBL2340331

NC(=O)NC1=NNCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13449252 0.79
SCHEMBL3856105 0.67
SCHEMBL15030744 0.66
Hydrochloric Acid SCHEMBL4707137 0.65
SCHEMBL7639495 0.64
SCHEMBL28413047 0.62
SCHEMBL18780818 0.60
SCHEMBL4538738 0.58
SCHEMBL4707208 0.58
SCHEMBL17140372 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210401989-A1 SEMI-SOLID, OIL-BASED PHARMACEUTICAL COMPOSITIONS CONTAINING PIRFENIDONE FOR APPLICATION IN TISSUE REPAIR EXCALIBUR PHARMACEUTICALS, INC. (US) 2021-12-30 US claimed
EP-3842030-A2 SEMI-SOLID, OIL-BASED PHARMACEUTICAL COMPOSITIONS CONTAINING PIRFENIDONE FOR APPLICATION IN TISSUE REPAIR EXCALIBUR PHARMACEUTICALS, INC. (US) 2021-06-30 EP claimed
EP-2825172-B1 PARALYTIC SHELLFISH POISON FOR THE TREATMENT OF ITCH ALGENIS SPA (CL) 2017-08-02 EP disclosed
US-9593120-B2 Paralytic shellfish poison ALGENIS SPA (CL) 2017-03-14 US disclosed
EP-2688548-B1 SKIN CARE COMPOSITION LAMBERTI SPA (IT) 2017-02-01 EP disclosed
US-20160000793-A1 SODIUM CHANNEL BLOCKER FOR TREATMENT OF LOSS OF SUPERFICIAL SENSITIVITY PHYTOTOX LIMITED (BM) 2016-01-07 US disclosed
US-9107925-B2 Sodium channel blocker for treatment of loss of superficial sensitivity PHYTOTOX LIMITED (BM) 2015-08-18 US disclosed
US-20150065528-A1 PARALYTIC SHELLFISH POISON ALGENIS SPA (CL) 2015-03-05 US disclosed
CN-104363915-A Paralytic shellfish poison PHYTOTOX SPA 2015-02-18 CN disclosed
EP-2825172-A1 PARALYTIC SHELLFISH POISON Algenis Spa (CL) 2015-01-21 EP disclosed
EP-2533785-B1 TREATMENT OF LOSS OF SENSE OF TOUCH WITH SAXITOXIN DERIVATIVES PHYTOTOX LTD (BM) 2014-04-23 EP disclosed
US-20140023600-A1 SKIN CARE COMPOSITION LAMBERTI SPA (IT) 2014-01-23 US disclosed
WO-2013135884-A1 PARALYTIC SHELLFISH POISON PHYTOTOX SPA (CL) 2013-09-19 WO disclosed
EP-2638908-A1 Paralytic Shellfish Poison Phytotox SpA (CL) 2013-09-18 EP disclosed
US-20130039976-A1 Sodium channel blocker for treatment of loss of superficial sensitivity PHYTOTOX LIMITED (BM) 2013-02-14 US disclosed
EP-2533785-A1 TREATMENT OF LOSS OF SENSE OF TOUCH WITH SAXITOXIN DERIVATIVES Phytotox Limited (BM) 2012-12-19 EP disclosed
US-8329200-B2 Water in oil emulsion has moisturizer of glycerol, chitosan, Fucogel, propylene glycol, polyoxyethylene glycol, dipropylene glycol, butylene glycol, mannitol, lactic acid, glycine,, sodium 2-pyrrolidone-5-carboxylate, hyaluronic acid, urea, and/or salts; storage stability; acne, wrinkle resistance BEIERSDORF AG (DE) 2012-12-11 US disclosed
WO-2011098539-A1 TREATMENT OF LOSS OF SENSE OF TOUCH WITH SAXITOXIN DERIVATIVES PHYTOTOX LIMITED (BM) 2011-08-18 WO disclosed
US-20050025729-A1 Lipstick BEIERSDORF AG 2005-02-03 US disclosed
US-20040258721-A1 Cosmetic or dermatological stick BEIERSDORF AG 2004-12-23 US disclosed