SCHEMBL23403418

SCHEMBL23403418

CCCn1nc(O)c(-c2ccc(C)cc2)c1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.39
GCGR P47871 1/20 0.39
USP7 Q93009 1/20 0.34
ALDH1A1 P00352 4/20 0.33
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 2/20 0.31
CYP2C19 P33261 2/20 0.31
RAB9A P51151 2/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 2/20 0.31
CYP2D6 P10635 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399501 0.92 GCGR (0.42) ESR1GCGRALDH1A1MEN1KMT2A
SCHEMBL23398497 0.88 GCGR (0.37) GCGRUSP7ALDH1A1MEN1KMT2A
SCHEMBL23399848 0.87 ESR1 (0.39) ESR1GCGRALDH1A1MEN1KMT2A
SCHEMBL23401896 0.84 GCGR (0.34) GCGRUSP7ALDH1A1MEN1KMT2A
SCHEMBL23403483 0.82 ESR1 (0.39) ESR1GCGRUSP7ALDH1A1ADORA2A
SCHEMBL23402997 0.81 ESR1 (0.38) ESR1GCGRUSP7ALDH1A1ADORA2A
SCHEMBL23401240 0.81 DPP4 (0.34) ESR1GCGRALDH1A1MEN1KMT2A
SCHEMBL23402959 0.80 GCGR (0.37) ESR1GCGRUSP7ALDH1A1MEN1
SCHEMBL23399842 0.80 ESR1 (0.44) ESR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL23400398 0.79 GRIA2 (0.41) ESR1GCGRUSP7ALDH1A1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed