SCHEMBL23403446

SCHEMBL23403446

CCCCn1ncc(O)c1CC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.36
SLC9A1 P19634 1/20 0.34
TYR P14679 1/20 0.33
TOP2A P11388 1/20 0.33
POLB P06746 1/20 0.33
AGTR1 P30556 1/20 0.32
NR1H3 Q13133 1/20 0.32
HCAR3 P49019 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402017 0.89 POLB (0.41) ESR1SLC9A1TYRPOLB
SCHEMBL23399858 0.87 ESR1 (0.35) ESR1SLC9A1TYRTOP2APOLB
SCHEMBL23399780 0.87 NPC1 (0.36) ESR1SLC9A1TYRTOP2APOLB
SCHEMBL23403604 0.83 ESR1 (0.33) ESR1SLC9A1
SCHEMBL23400969 0.80 HTT (0.38) ESR1POLB
SCHEMBL23403406 0.80 POLB (0.38) ESR1TYRPOLB
SCHEMBL23401337 0.79 POLB (0.44) ESR1SLC9A1TYRPOLBNR1H3
SCHEMBL27737816 0.76 NR4A3 (0.51) AGTR1HCAR3
SCHEMBL23399649 0.76
SCHEMBL23403175 0.76 POLB (0.40) ESR1SLC9A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed