Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339450 | 1.00 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL2339444 | 1.00 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL14832682 | 1.00 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL2339937 | 1.00 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL32678164 | 0.89 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL2340691 | 0.86 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL2339415 | 0.86 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL2337013 | 0.86 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL2337010 | 0.86 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APPM1B | |
| SCHEMBL8891623 | 0.84 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2APPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358714-A1 | ALKYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES | F. Hoffmann-La Roche AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010057795-A1 | ALKYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-27 | — | — | WO | disclosed |