SCHEMBL23405649

SCHEMBL23405649

C[C@]1(O)C[C@H]2COC[C@@H](C1)N2Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.45
CHRM4 P08173 1/20 0.45
CHRM5 P08912 1/20 0.45
OPRK1 P41145 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.40
NR1H2 P55055 1/20 0.40
TMEM97 Q5BJF2 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
LTA4H P09960 1/20 0.38
FUCA1 P04066 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23405650 1.00 CHRM2 (0.45) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL12219688 1.00 CHRM2 (0.45) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL21462353 1.00 CHRM2 (0.45) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL2841484 0.86 CHRM2 (0.49) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL2841486 0.86 CHRM2 (0.49) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL4477292 0.86 CHRM2 (0.49) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL12193988 0.84 CHRM2 (0.42) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL16237890 0.84 CHRM2 (0.44) CHRM2CHRM4CHRM5OPRK1L3MBTL1
SCHEMBL636999 0.82 CHRM2 (0.58) CHRM2CHRM4CHRM5L3MBTL1KMT2A
SCHEMBL16237639 0.79 GRM6 (0.52) CHRM2CHRM4CHRM5OPRK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729127-A2 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2026-04-22 EP disclosed
US-20260042776-A1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2026-02-12 US disclosed
US-12486285-B2 BCL6 inhibitors CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2025-12-02 US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 US disclosed
EP-4201939-A1 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2023-06-28 EP disclosed
EP-3774817-B1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-12-07 EP disclosed
US-11512095-B2 BCL6 inhibitors THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2022-11-29 US disclosed
US-20210163497-A1 BCL6 INHIBITORS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2021-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163497-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 CHRM2 4751/4885CHRM4 4697/4885CHRM5 4734/4885
US-20230287003-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 CHRM2 4751/4885CHRM4 4697/4885CHRM5 4734/4885
US-12486285-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 CHRM2 4751/4885CHRM4 4697/4885CHRM5 4734/4885
US-11512095-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 CHRM2 4751/4885CHRM4 4697/4885CHRM5 4734/4885
US-20260042776-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL9 CHRM2 4733/4885CHRM4 4720/4885CHRM5 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.