⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675934 | 0.79 | — | — | |
| SCHEMBL1803417 | 0.77 | — | — | |
| SCHEMBL6141144 | 0.77 | HSD17B10 (0.30) | — | |
| SCHEMBL8965511 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL14299775 | 0.77 | HSD17B10 (0.30) | — | |
| SCHEMBL637752 | 0.76 | — | — | |
| SCHEMBL5277179 | 0.75 | — | — | |
| SCHEMBL1618584 | 0.74 | HSD17B10 (0.32) | — | |
| SCHEMBL5698862 | 0.74 | — | — | |
| SCHEMBL5222367 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743492-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | claimed |
| EP-3006599-B1 | METHOD FOR COATING THE SURFACE OF A METAL SUBSTRATE | SAFRAN LANDING SYSTEMS (FR) | 2019-03-27 | — | — | EP | claimed |
| US-10066301-B2 | Method of coating the surface of a metal substrate | MESSIER-BUGATTI-DOWTY (FR) | 2018-09-04 | — | — | US | claimed |
| US-20160102406-A1 | METHOD OF COATING THE SURFACE OF A METAL SUBSTRATE | MESSIER-BUGATTI-DOWTY (FR) | 2016-04-14 | — | — | US | claimed |
| EP-3006599-A1 | METHOD FOR COATING THE SURFACE OF A METAL SUBSTRATE | Messier-Bugatti-Dowty (FR) | 2016-04-13 | — | — | EP | claimed |
| EP-2024406-B1 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2012-08-01 | — | — | EP | claimed |
| US-8124689-B2 | Silicone acrylate hybride composition and method of making same | DOW CORNING CORPORATION (US) | 2012-02-28 | — | — | US | claimed |
| US-20090196911-A1 | Silicone Acrylate Hybride Composition and Method Of Making Same | DOW SILICONES CORPORATION | 2009-08-06 | — | — | US | claimed |
| EP-2024406-A2 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING CORPORATION (US) | 2009-02-18 | — | — | EP | claimed |
| WO-2007145996-A9 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2007145996-A2 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING CORPORATION (US) | 2007-12-21 | — | — | WO | claimed |
| EP-1469002-A1 | Method for stabilizing unsaturated organo-silicon compounds | Wacker-Chemie GmbH (DE) | 2004-10-20 | — | — | EP | claimed |
| EP-4395749-B1 | TRANSDERMAL THERAPEUTIC SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF GUANFACINE COMPRISING GUANFACINE AND A MONO-CARBOXYLIC ACID | LTS LOHMANN THERAPIE SYSTEME AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-3996692-B1 | TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING AN ACTIVE AGENT-CONTAINING LAYER COMPRISING A SILICONE-CONTAINING POLYMER AND A SKIN CONTACT LAYER COMPRISING A SILICONE GEL ADHESIVE | LTS LOHMANN THERAPIE SYSTEME AG (DE) | 2025-06-11 | — | — | EP | disclosed |
| US-12214088-B2 | Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2025-02-04 | — | — | US | disclosed |
| US-12168074-B2 | Transdermal therapeutic system for the transdermal administration of guanfacine comprising a silicone polymer | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2024-12-17 | — | — | US | disclosed |
| US-20020115878-A1 | METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP | DOW TORAY CO., LTD. (JP) | 2002-08-22 | — | — | US | disclosed |
| EP-0486279-B2 | Process for removing acidic impurities from alkoxysilanes | SHINETSU CHEMICAL CO (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5247117-A | Neutralization with sterically hindered alcohols or amines, distillation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0486279-A1 | Process for removing acidic impurities from alkoxysilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |