Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18809943 | 0.94 | BTK (0.52) | BTKRPS6KB1KCNH2CHEK1EGFR | |
| SCHEMBL19257841 | 0.94 | BTK (0.52) | BTKRPS6KB1KCNH2CHEK1EGFR | |
| SCHEMBL22737476 | 0.94 | BTK (0.56) | BTKLCKSRC | |
| SCHEMBL23223089 | 0.93 | BTK (0.51) | BTKRPS6KB1KCNH2CHEK1EGFR | |
| SCHEMBL22909562 | 0.92 | BTK (0.53) | BTKKCNH2 | |
| SCHEMBL20881645 | 0.86 | BTK (0.50) | BTKKCNH2 | |
| SCHEMBL24041268 | 0.86 | BTK (0.58) | BTKKCNH2EGFR | |
| SCHEMBL25472788 | 0.85 | BTK (0.56) | BTKLCKSRCEGFR | |
| SCHEMBL25468816 | 0.85 | BTK (0.47) | BTKRPS6KB1 | |
| SCHEMBL22737427 | 0.84 | BTK (0.57) | BTKLCKSRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |