Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413411 | 0.93 | KRAS (0.78) | KRAS | |
| SCHEMBL29903121 | 0.92 | KRAS (0.65) | KRAS | |
| SCHEMBL23409291 | 0.92 | KRAS (0.65) | KRAS | |
| SCHEMBL23413711 | 0.90 | KRAS (0.64) | KRAS | |
| SCHEMBL29595093 | 0.88 | KRAS (0.87) | KRAS | |
| SCHEMBL26964838 | 0.88 | KRAS (0.87) | KRAS | |
| SCHEMBL23409267 | 0.88 | KRAS (0.87) | KRAS | |
| SCHEMBL26623690 | 0.86 | KRAS (0.74) | KRAS | |
| SCHEMBL29344952 | 0.85 | KRAS (0.72) | KRAS | |
| SCHEMBL30998522 | 0.85 | KRAS (0.60) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106231-A1 | A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021107160-A1 | A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-03 | — | — | WO | disclosed |