Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890562 | 0.83 | TSHR (0.42) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL27520159 | 0.81 | TSHR (0.41) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL27788816 | 0.79 | TSHR (0.39) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL8084218 | 0.77 | — | — | |
| SCHEMBL10499840 | 0.77 | TSHR (0.50) | TSHRTRPV1CHRM2CHRM4CHRM1 | |
| SCHEMBL28500937 | 0.76 | TSHR (0.41) | CYP2C9TSHRACACBMEN1KMT2A | |
| SCHEMBL8084391 | 0.76 | CYP2C9 (0.45) | CYP2C9ACACBMEN1KMT2APSMB5 | |
| SCHEMBL8076302 | 0.76 | CYP2C9 (0.45) | CYP2C9TSHRACACBMEN1KMT2A | |
| SCHEMBL3376216 | 0.73 | — | — | |
| SCHEMBL9292556 | 0.73 | TSHR (0.46) | TSHRTRPV1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108649-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |