SCHEMBL23415525

SCHEMBL23415525

CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CCC(CO)=C[C@@H]21

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 0.86
CNR1 P21554 13/20 0.86
ABHD12 Q8N2K0 3/20 0.78
ABHD6 Q9BV23 3/20 0.78
FAAH O00519 2/20 0.78
DRD3 P35462 2/20 0.78
TRPM8 Q7Z2W7 2/20 0.78
GPR55 Q9Y2T6 2/20 0.78
NR1I2 O75469 1/20 0.78
LDHA P00338 1/20 0.78
GLRA1 P23415 1/20 0.78
GPR183 P32249 1/20 0.78
ENPP2 Q13822 1/20 0.78
GPR18 Q14330 1/20 0.78
MEN1 O00255 1/20 0.72
KMT2A Q03164 1/20 0.72
TRPA1 O75762 1/20 0.66
HTR1A P08908 1/20 0.66
TRPV1 Q8NER1 1/20 0.66
TRPV3 Q8NET8 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21363770 1.00 CNR2 (0.86) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL31546115 1.00 CNR2 (0.86) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL20763968 1.00 CNR2 (0.86) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL997050 1.00 CNR2 (0.86) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL31545117 0.93 CNR2 (0.78) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL22095410 0.93 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL20763972 0.93 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL31544994 0.93 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL21363560 0.93 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL31544941 0.93 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021102514-A1 MORAXELLA TREATMENT USING CANNABINOIDS Botanix Pharmaceuticals Limited (AU) 2021-06-03 WO disclosed
WO-2021102515-A1 ANTIBACTERIAL TREATMENT USING A CANNABINOID AND AN ACTIVE AGENT Botanix Pharmaceuticals Limited (AU) 2021-06-03 WO disclosed
WO-2021102516-A1 NEISSERIA TREATMENT USING CANNABINOIDS Botanix Pharmaceuticals Limited (AU) 2021-06-03 WO disclosed
WO-2021102513-A1 LEGIONELLA TREATMENT USING CANNABINOIDS Botanix Pharmaceuticals Limited (AU) 2021-06-03 WO disclosed