Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15219273 | 0.79 | KDM4C (0.38) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL442421 | 0.78 | KDM4C (0.46) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL23416925 | 0.78 | KDR (0.43) | KDM4CMEN1KMT2ACNR1KDR | |
| SCHEMBL10498353 | 0.77 | KDM4C (0.34) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL11919035 | 0.75 | IDO1 (0.36) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL11916028 | 0.75 | KDM4C (0.35) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL2804255 | 0.74 | KDM4C (0.40) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL17694181 | 0.72 | KDM4C (0.40) | KDM4CHDAC1HDAC6CDK5CDK5R1 | |
| SCHEMBL21143892 | 0.71 | KDM4C (0.38) | KDM4CMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL24054273 | 0.71 | KDM4C (0.41) | KDM4CMEN1KMT2AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058961-A1 | SUBSTITUTED HETEROCYCLICS WITH THERAPEUTIC ACTIVITY IN HIV | NATIONAL INSTITUTES OF HEALTH | 2023-02-23 | — | — | US | disclosed |
| WO-2021102114-A1 | SUBSTITUTED HETEROCYCLICS WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230058961-A1 | SUBSTITUTED HETEROCYCLICS WITH THERAPEUTIC ACTIVITY IN HIV | CD4, NFATC1, PAICS | KDM4C 1440/4885MEN1 4531/4885KMT2A 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.