Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | ECE1 | P42892 | 11/20 | 0.53 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29861670 | 0.91 | CTSC (0.58) | CTSCACEECE1MAGI3ERAP2 | |
| SCHEMBL29861416 | 0.90 | ACE (0.61) | CTSCACEECE1 | |
| SCHEMBL30567428 | 0.90 | ACE (0.61) | CTSCACEECE1MAGI3ERAP2 | |
| SCHEMBL30051277 | 0.89 | CTSC (0.64) | CTSCACEECE1MAGI3ERAP2 | |
| SCHEMBL30051305 | 0.86 | ACE (0.72) | CTSCACEECE1ERAP2 | |
| SCHEMBL30051632 | 0.85 | CTSC (0.60) | CTSCACEECE1MAGI3ERAP2 | |
| SCHEMBL30052446 | 0.84 | ACE (0.59) | CTSCACEECE1ERAP2 | |
| SCHEMBL30053239 | 0.84 | CTSC (0.66) | CTSCACEECE1ERAP2MMP9 | |
| Valyltryptophan SCHEMBL150532 | 0.84 | ACE (0.75) | CTSCACEECE1 | |
| Valyltryptophan SCHEMBL29365770 | 0.84 | ACE (0.75) | CTSCACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |