Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089861 | 0.85 | MAPK1 (0.44) | MAPTMAPK1TP53KDM4EPTGER4 | |
| SCHEMBL16682715 | 0.80 | MAPT (0.43) | MAPTMAPK1TP53KDM4EPTGER4 | |
| SCHEMBL1161278 | 0.73 | MAPT (0.48) | MAPTMAPK1TP53KDM4EPTGER4 | |
| SCHEMBL31172637 | 0.72 | KLKB1 (0.46) | MAPTMAPK1TP53KDM4EPTGER4 | |
| SCHEMBL13933139 | 0.72 | CYP1A2 (0.62) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6509581 | 0.72 | KDM4E (0.50) | MAPK1KDM4EPTGER4ALDH1A1CYP1A2 | |
| SCHEMBL16372000 | 0.72 | LCK (0.47) | MAPTMAPK1TP53KDM4EPTGER4 | |
| SCHEMBL29549633 | 0.72 | MAPT (0.55) | MAPTMAPK1TP53KDM4EALDH1A1 | |
| SCHEMBL23554282 | 0.72 | MAPT (0.55) | MAPTMAPK1TP53KDM4EALDH1A1 | |
| SCHEMBL31273956 | 0.71 | PTGER4 (0.43) | MAPTMAPK1TP53KDM4EPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102161-A1 | METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | ANGION BIOMEDICA CORP. (US) | 2021-05-27 | — | — | WO | disclosed |