Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24895182 | 1.00 | HPGD (0.42) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| SCHEMBL29736139 | 1.00 | HPGD (0.42) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| SCHEMBL23423078 | 1.00 | HPGD (0.42) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| SCHEMBL23423077 | 1.00 | HPGD (0.42) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| Trifluoroacetic Acid SCHEMBL23389935 | 0.95 | KCNQ3 (0.39) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| Trifluoroacetic Acid SCHEMBL23389687 | 0.95 | KCNQ3 (0.39) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| SCHEMBL1289727 | 0.77 | RECQL (0.51) | HPGDLMNAKCNQ3KCNQ2RECQL | |
| SCHEMBL23423071 | 0.77 | — | — | |
| SCHEMBL23423202 | 0.76 | MEN1 (0.39) | HPGDLMNAUSP2CYP3A4TSHR | |
| SCHEMBL23423035 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021101836-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-05-27 | — | — | WO | disclosed |