SCHEMBL23425409

SCHEMBL23425409

COc1ccc(C(OC[C@@]23CO[C@@H]([C@H](n4cnc5c(=O)[nH]c(/N=C/N(C)C)nc54)O2)[C@@H]3P(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3033241 0.91 TYMP (0.34) TYMP
SCHEMBL23425438 0.87 KDM4E (0.36) TYMP
SCHEMBL22556249 0.84 TYMP (0.45) TYMP
SCHEMBL31359570 0.84 TYMP (0.45) TYMP
SCHEMBL22594612 0.84 TYMP (0.45) TYMP
SCHEMBL22556252 0.84 TYMP (0.45) TYMP
SCHEMBL19825396 0.84 TYMP (0.30) TYMP
SCHEMBL19817402 0.84 TYMP (0.30) TYMP
SCHEMBL19815204 0.84 TYMP (0.30) TYMP
SCHEMBL23827226 0.83 TYMP (0.34) TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021503-B2 Process for GalNAc oligonucleotide conjugates HOFFMANN-LA ROCHE INC. (US) 2021-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11021503-B2 Process for GalNAc oligonucleotide conjugates CSGALNACT1, ALG1, ALG8 TYMP 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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