SCHEMBL23430233

SCHEMBL23430233

CN/C=N\CCC[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](CS)NC(=O)CN1C(=O)N[C@H](C)C1=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 11/20 0.50
▸ KISS1R Q969F8 3/20 0.48
▸ CCKBR P32239 3/20 0.47
▸ MC4R P32245 2/20 0.46
▸ NPBWR1 P48145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23430185 0.94 IL23R (0.49) IL23RKISS1RCCKBRMC4RNPBWR1
SCHEMBL23430184 0.93 IL23R (0.48) IL23RKISS1RCCKBRMC4R
SCHEMBL23430118 0.91 IL23R (0.51) IL23RKISS1RCCKBRMC4RNPBWR1
SCHEMBL23430235 0.90 IL23R (0.49) IL23RKISS1RCCKBRMC4RNPBWR1
SCHEMBL20108414 0.88 MC4R (0.59) MC4R
SCHEMBL23430224 0.88 MC4R (0.59) MC4R
SCHEMBL20108543 0.86 IL23R (0.49) IL23RKISS1RCCKBRNPBWR1
SCHEMBL23430107 0.86 IL23R (0.51) IL23RKISS1RCCKBR
SCHEMBL23430108 0.86 IL23R (0.51) IL23RKISS1RCCKBR
SCHEMBL20108335 0.86 IL23R (0.48) IL23RKISS1RCCKBRNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163536-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN IPSEN PHARMA SAS (FR) 2021-06-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163536-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN MC4R, MC3R, MC1R IL23R 420/4885KISS1R 87/4885CCKBR 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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