SCHEMBL234359

SCHEMBL234359

CCOC(=O)C=C(C(=O)OCC)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.59
HCAR2 Q8TDS4 1/20 0.41
GLO1 Q04760 1/20 0.39
ALDH1A1 P00352 4/20 0.36
CYP2D6 P10635 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PRKCA P17252 1/20 0.34
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234358 1.00 NPSR1 (0.59) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL28432838 0.86 NPSR1 (0.57) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL16160202 0.85 NPSR1 (0.48) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL9360096 0.82 NPSR1 (0.42) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL9360094 0.82 NPSR1 (0.42) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL28181560 0.82 NPSR1 (0.52) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL10725795 0.82 NPSR1 (0.52) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL6129228 0.81 HCAR2 (0.44) NPSR1HCAR2ALDH1A1SMN1; SMN2TSHR
SCHEMBL6129227 0.81 HCAR2 (0.44) NPSR1HCAR2ALDH1A1SMN1; SMN2TSHR
SCHEMBL10725805 0.80 NPSR1 (0.50) NPSR1HCAR2GLO1ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed