Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 17/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27822651 | 0.98 | MC4R (0.53) | MC4RKCNQ2CYP3A4GAAABCC8 | |
| D-Glutamate SCHEMBL27876703 | 0.89 | MC4R (0.49) | MC4RKCNQ2CYP3A4GAAABCC8 | |
| SCHEMBL390826 | 0.87 | MC4R (0.54) | MC4RKCNQ2CYP3A4GAA | |
| SCHEMBL442668 | 0.87 | MC4R (0.54) | MC4RKCNQ2CYP3A4GAA | |
| SCHEMBL17871701 | 0.87 | MC4R (0.54) | MC4RKCNQ2CYP3A4GAA | |
| SCHEMBL1964089 | 0.87 | MC4R (0.54) | MC4RKCNQ2CYP3A4GAA | |
| SCHEMBL31388217 | 0.87 | MC4R (0.54) | MC4RKCNQ2CYP3A4GAA | |
| SCHEMBL31128130 | 0.87 | MC4R (0.54) | MC4RKCNQ2CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL17871800 | 0.86 | MC4R (0.53) | MC4RKCNQ2CYP3A4GAA | |
| SCHEMBL5792053 | 0.85 | MC4R (0.55) | MC4RKCNQ2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358369-A1 | Process for the preparation of substantially optically pure repaglinide and precursors thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010046360-A1 | PROCESS FOR THE PREPARATION OF SUBSTANTIALLY OPTICALLY PURE REPAGLINIDE AND PRECURSORS THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177221-A1 | Process for the preparation of substantially optically pure Repaglinide and precursors thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2010-04-21 | — | — | EP | disclosed |