Sergliflozin A

Sergliflozin A

SCHEMBL23436839

COc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)C2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 19/20 1.00
▸ SLC5A1 P13866 11/20 1.00
▸ ACHE P22303 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sergliflozin A SCHEMBL2574820 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ACHE
Sergliflozin A SCHEMBL4361463 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ACHE
SCHEMBL5524027 0.91 SLC5A2 (0.83) SLC5A2SLC5A1
SCHEMBL5524039 0.91 SLC5A2 (0.83) SLC5A2SLC5A1
SCHEMBL12808056 0.90 SLC5A2 (0.82) SLC5A2SLC5A1
SCHEMBL2577291 0.89 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL4355721 0.89 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL14634631 0.88 SLC5A2 (0.81) SLC5A2SLC5A1ACHE
SCHEMBL29687640 0.88 SLC5A2 (0.81) SLC5A2SLC5A1ACHE
SCHEMBL2574895 0.88 SLC5A2 (0.79) SLC5A2SLC5A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210161930-A1 USE OF SGLT-2 INHIBITORS IN THE DRYING-OFF OF NON-HUMAN MAMMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2021-06-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210161930-A1 USE OF SGLT-2 INHIBITORS IN THE DRYING-OFF OF NON-HUMAN MAMMALS SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885SLC5A1 2/4885ACHE 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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