SCHEMBL2344121

SCHEMBL2344121

COc1cccc(OC)c1C(=O)C(C(=O)c1c(OC)cccc1OC)C(C)(C)CC(C)Cp1oo1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.33
GAA P10253 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 2/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ATM Q13315 1/20 0.32
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131005 0.82 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL28239957 0.80 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL15362 0.80 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL134377 0.79 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL4819660 0.78 CA12 (0.35) CA12CA1CA2CA7CA9
SCHEMBL20544420 0.76 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL1663849 0.76 CA12 (0.39) CA12CA1CA2CA7CA9
SCHEMBL58176 0.75 CA12 (0.38) CA12CA1CA2CA7CA9
Benzoic Acid SCHEMBL28208456 0.74 MRGPRX4 (0.40) CA12CA1CA2CA7CA9
SCHEMBL14655798 0.70 CA12 (0.52) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9170558-B2 Image forming apparatus and process cartridge including a cleaning blade which includes a cured composition RICOH COMPANY, LTD. (JP) 2015-10-27 US disclosed
US-20150071678-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2015-03-12 US disclosed
US-20110261443-A1 HEAT RAY REFLECTIVE FILM AND LAMINATE THEREOF, AND COATING FLUID FOR FORMING HEAT RAY REFLECTIVE LAYER MITSUBISHI CHEMICAL CORPORATION (JP) 2011-10-27 US disclosed
EP-2361893-A1 HEAT RAY REFLECTIVE FILM AND LAMINATED PRODUCT THEREOF, AND COATING SOLUTION FOR FORMING HEAT RAY REFLECTIVE LAYER Mitsubishi Chemical Corporation (JP) 2011-08-31 EP disclosed