Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23420457 | 0.93 | EGFR (0.82) | EGFR | |
| SCHEMBL23420381 | 0.92 | EGFR (0.82) | EGFR | |
| SCHEMBL25001540 | 0.92 | EGFR (0.79) | EGFR | |
| SCHEMBL22950985 | 0.91 | EGFR (0.80) | EGFR | |
| SCHEMBL29857904 | 0.91 | EGFR (0.80) | EGFR | |
| SCHEMBL23441956 | 0.91 | EGFR (0.78) | EGFR | |
| SCHEMBL23420455 | 0.90 | EGFR (0.79) | EGFR | |
| SCHEMBL23441963 | 0.90 | EGFR (0.63) | EGFR | |
| SCHEMBL23420475 | 0.90 | EGFR (0.78) | EGFR | |
| SCHEMBL23441966 | 0.90 | EGFR (0.67) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104441-A1 | POLYAROMATIC COMPOUND AS EGFR KINASE INHIBITOR | 江苏先声药业有限公司 | 2021-06-03 | — | — | WO | disclosed |