Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.73 |
| ▸ | CA2 | P00918 | 10/20 | 0.73 |
| ▸ | CA9 | Q16790 | 8/20 | 0.73 |
| ▸ | CA5A | P35218 | 6/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.73 |
| ▸ | CA6 | P23280 | 4/20 | 0.73 |
| ▸ | CA7 | P43166 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | CA4 | P22748 | 3/20 | 0.73 |
| ▸ | NT5E | P21589 | 1/20 | 0.73 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27543069 | 0.96 | CA1 (0.67) | CA1CA2CA9CA5ACA5B | |
| Sulfamate SCHEMBL2545884 | 0.85 | CA1 (1.00) | CA1CA2CA9CA5ACA5B | |
| Sulfamate SCHEMBL11400 | 0.85 | — | — | |
| Sulfamate SCHEMBL285371 | 0.85 | — | — | |
| Benzene SCHEMBL27613221 | 0.84 | CA1 (0.50) | CA1CA2CA9CA5ACA5B | |
| Sulfamate SCHEMBL27301417 | 0.82 | CA1 (0.73) | CA1CA2CA9CA5ACA5B | |
| Sulfamate SCHEMBL5187482 | 0.82 | — | — | |
| Sulfamate SCHEMBL23581784 | 0.80 | — | — | |
| Sulfamate SCHEMBL20874504 | 0.80 | — | — | |
| Sulfamate SCHEMBL11115704 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117264175-A | Polyisocyanate composition, aqueous coating composition, coated substrate, and method for producing polyisocyanate composition | 旭化成株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-117229476-A | Polyisocyanate composition, blocked polyisocyanate composition, polyurethane resin composition, coating composition, and coated substrate | 旭化成株式会社 | 2023-12-15 | — | — | CN | disclosed |
| US-20230265087-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint, Inc. | 2023-08-24 | — | — | US | disclosed |
| US-11613534-B2 | Small molecule activators of Tie-2 | EyePoint Pharmaceuticals, Inc. (US) | 2023-03-28 | — | — | US | disclosed |
| US-20210353568-A1 | DERMATOLOGIC TOPICAL APPLICATIONS OF ROR GAMMA AND ROR GAMMA-T INHIBITORS FOR THE PREVENTION OF SKIN CANCER DEVELOPMENT | YALE UNIVERSITY (US) | 2021-11-18 | — | — | US | disclosed |
| US-20210147404-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | EyePoint, Inc. | 2021-05-20 | — | — | US | disclosed |
| WO-2021086904-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | Aerpio Pharmaceuticals, Inc. (US) | 2021-05-06 | — | — | WO | disclosed |
| WO-2020061024-A1 | DERMATOLOGIC TOPICAL APPLICATIONS OF ROR GAMMA AND ROR GAMMA-T INHIBITORS FOR THE PREVENTION OF SKIN CANCER DEVELOPMENT | YALE UNIVERSITY (US) | 2020-03-26 | — | — | WO | disclosed |
| CN-104428292-B | Phenylalkyl sulfamate compound and muscle relaxant composition comprising same | 生物药品解决方案有限公司 | 2017-02-08 | — | — | CN | disclosed |
| EP-2584399-B1 | TRANSFLECTIVE LIQUID-CRYSTAL DISPLAY DEVICE | TOPPAN PRINTING CO LTD (JP) | 2016-02-24 | — | — | EP | disclosed |
| CN-100366685-C | Water-base black ink composition and colored material | NIPPON KAYAKU KK (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-101054352-A | New strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-10-17 | — | — | CN | disclosed |
| CN-1981004-A | Inkjet black ink, ink set, inkjet recording method, ink cartridge, recording unit, and inkjet recorder | CANON KK (JP) | 2007-06-13 | — | — | CN | disclosed |
| CN-1756812-A | aqueous black ink composition and colored article | NIPPON KAYAKU KK (JP) | 2006-04-05 | — | — | CN | disclosed |
| US-20050196658-A1 | proton-conducting electrolyte that has excellent proton-conducting properties, heat resistance, and chemical stability without containing any fluorine. The proton-conducting electrolyte contains polyamide sulfamidic acid in which a polyamide backbone has side chains of sulfamidic acid groups | SAMSUNG SDI CO., LTD. (KR) | 2005-09-08 | — | — | US | disclosed |
| US-6369092-B1 | Method for treating neoplasia by exposure to substituted benzimidazole derivatives | CELL PATHWAYS, INC. | 2002-04-09 | — | — | US | disclosed |
| US-5464731-A | HAVING IMPROVED BACKGROUND AND GRADATION | FUJI PHOTO FILM CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0467710-A2 | Method for treating Parkinson's disease employing the ATP-sensitive potassium channel blocker quinine | E.R. SQUIBB & SONS, INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-4714700-A | TRANQUILIZERS, ANXIOLYTIC AGENTS | CHOAY S.A. (FR) | 1987-12-22 | — | — | US | disclosed |
| US-4567134-A | NO WATER WASHING AFTER FIXING | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147404-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | TIE1, TEK, KDR | CA1 4801/4885CA2 3100/4885CA9 4662/4885 |
| US-11613534-B2 | Small molecule activators of Tie-2 | TIE1, TEK, KDR | CA1 4801/4885CA2 3100/4885CA9 4662/4885 |
| US-20230265087-A1 | SMALL MOLECULE ACTIVATORS OF TIE-2 | TIE1, TEK, KDR | CA1 4801/4885CA2 3100/4885CA9 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.