Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18732865 | 1.00 | KMT2A (0.54) | KMT2ATLR2TLR1MDM2CASP3 | |
| SCHEMBL23446481 | 0.96 | KMT2A (0.57) | KMT2ATLR2TLR1MDM2CASP3 | |
| SCHEMBL24235786 | 0.92 | KMT2A (0.64) | KMT2ATLR2CASP3 | |
| SCHEMBL27261267 | 0.89 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2MAPT | |
| SCHEMBL30783495 | 0.89 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2MAPT | |
| SCHEMBL732427 | 0.88 | KMT2A (0.68) | KMT2ATLR2TLR1MDM2 | |
| SCHEMBL2736294 | 0.88 | TLR2 (0.53) | KMT2ATLR2TLR1MDM2MAPT | |
| SCHEMBL15750412 | 0.88 | KMT2A (0.53) | KMT2ATLR2TLR1MDM2MEN1 | |
| SCHEMBL2947901 | 0.88 | KMT2A (0.53) | KMT2ATLR2TLR1MDM2CASP3 | |
| SCHEMBL1738182 | 0.88 | MDM2 (0.59) | KMT2ATLR2TLR1MDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022022360-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, AND PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2022-02-03 | — | — | WO | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |