Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 12/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 4/20 | 0.48 |
| ▸ | PLAU | P00749 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23424051 | 0.82 | CHEK2 (0.48) | CHEK2HDAC6PLGPLAUBRD4 | |
| SCHEMBL23153401 | 0.81 | CHEK2 (0.63) | CHEK2HDAC6 | |
| SCHEMBL21017933 | 0.80 | BRD4 (0.47) | CHEK2HDAC6PLGPLAUBRD4 | |
| SCHEMBL1233400 | 0.80 | CHEK2 (0.58) | CHEK2HDAC6PLGPLAU | |
| SCHEMBL23424094 | 0.80 | BRD4 (0.47) | CHEK2HDAC6BRD4 | |
| SCHEMBL20982733 | 0.80 | CHEK2 (0.58) | CHEK2HDAC6 | |
| SCHEMBL16586762 | 0.79 | CHEK2 (0.58) | CHEK2HDAC6PLGPLAU | |
| SCHEMBL16586792 | 0.79 | CHEK2 (0.57) | CHEK2HDAC6PLGPLAU | |
| SCHEMBL21017942 | 0.78 | HDAC6 (0.58) | CHEK2HDAC6 | |
| SCHEMBL12888578 | 0.78 | CHEK2 (0.55) | CHEK2HDAC6PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105887-A1 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP BIOTECH GMBH (DE) | 2021-06-03 | — | — | WO | disclosed |