Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911675 | 1.00 | TSHR (0.34) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL19705300 | 1.00 | TSHR (0.34) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL6974952 | 0.86 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL9910565 | 0.86 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL17972374 | 0.86 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL15489375 | 0.86 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL9910569 | 0.86 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL17976699 | 0.83 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL12721725 | 0.83 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 | |
| SCHEMBL12721734 | 0.83 | TSHR (0.36) | TSHROGACHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108649-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |