Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 4/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194169 | 0.98 | SPHK1 (0.48) | SPHK2SPHK1F2PRSS1KDM5A | |
| Hydrochloric Acid SCHEMBL11579730 | 0.91 | SPHK2 (0.39) | SPHK2SPHK1F2PRSS1KDM5A | |
| SCHEMBL22427018 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL10706288 | 0.80 | SPHK1 (0.50) | SPHK2SPHK1LMNAMAPK1HTT | |
| Hydrochloric Acid SCHEMBL10706284 | 0.80 | SPHK1 (0.50) | SPHK2SPHK1LMNAMAPK1HTT | |
| SCHEMBL4188390 | 0.78 | KMT2A (0.52) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL1457135 | 0.76 | KDM5A (0.50) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL7762713 | 0.76 | KDM5A (0.50) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL6606128 | 0.76 | KDM5A (0.50) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL7851689 | 0.76 | SPHK2 (0.67) | SPHK2SPHK1F2PRSS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106988-A1 | G9a INHIBITOR | 杏林製薬株式会社 | 2021-06-03 | — | — | WO | disclosed |